Three 6 Mafia's Gangsta Boo Dead at 43, Possible Overdose

Gallery Launch Gallery Remembering Gangsta Boo Launch Gallery Gallery Getty

4:53 PM PT -- Sources connected to Gangsta Boo tell TMZ ... the rapper's death appears to be drug-related. We're told Gangsta was with her brother last night at a local concert in Memphis, and that her sibling started to overdose sometime in the night ... requiring hospitalization.

While he ended up being okay, our sources tell us that people familiar with Gangsta Boo's death scene insist narcotics were found on her person and that a fentanyl-laced substance is believed to be at play. We're told the police are launching an official investigation.

An autopsy obviously needs to be done as well to see what the cause of death is.

Lola Mitchell, AKA Gangsta Boo -- a former member of Three 6 Mafia and a pioneer of female rap -- has died.

The hip hop star's passing was confirmed by her former labelmate DJ Paul -- who threw up a photo of her on IG ... seemingly as a tribute. Several prominent artists commented with messages of condolences. The exact circumstances surrounding her death are unknown.

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